From what I heard, Regeneration only comes with enough gimmicks for like 20 or so performances (I'm not really sure), so once that's up, you done, no more, so I wouldn't go for that one.
Smoke is pretty good, and gets great reactions, and you can use it and combine it with many routines, but you also need charge the gimmick and buy refills eventually, so it's not always ready to go (unlike the deck of cards for example).
Crush is pretty impractical, so I wouldn't go for that one either.
Edge is pretty much a one revelation with one deck of cards, two revelations the most, which means it cannot be done more than twice for the same audience (which is pretty much all you need), and it's all in the hands as it doesn't require a table (I believe).
Spreadwave is what I would go for because it's not just an ordinary card trick, selection is free, revelation is pretty stunning and visual, and it fooled Pen and Teller. The only downside is that you need a lot of table space.