Actually I'm a lefty with both cards and coins.
I think southpaws who have been successful in magic, have really had to overcome a major learning curve that would discourage most others. We have to dedicate ourselves to watch/read the learning medium we're studying and then process it backwards in order to retain it. This changes the way we look at the world, not just in magic. This often does alter the creative process, but doesn't give the left handed magician/person any advantage over anyone else.
As far as creativity goes, here's an exercise I invite you all to try. I promise this will get your creative juices flowing. Pick up any magic book, instead of looking through the method, read and re-read the description of the effect. Imagine that you were viewing that effect for the very first time w/ your "Spectator Cap" on. After you've imagined the moments of astonishment, only then do you conjure your own methods to achieve the same effect. Use all the techniques and gimmicks you already have knowledge of, and have access to.
Once you're satisfied w/ your own method, only then read the published method to see how close you came. Perhaps you can combine your method w/ the published method to come up with something completely new. It's a technique that I've employed over the years, and I certainly invite you to do the same.
E-Roc